![]() Veterans with Gulf War Illness have long struggled to get a proper diagnosis and treatment, despite experiencing symptoms for several decades. However, a rival hypothesis suggests mitochondria - the energy-producing organelle found in most cells - may be the true source of the symptoms. The prevailing notion is that inflammation is the driving force of the symptoms, as inflammatory markers are modestly higher in affected veterans than in healthy controls. However, its exact mechanism in the body continues to be debated, making it difficult to diagnose and treat. The condition is believed to have been triggered by veterans’ exposure to environmental toxins. ![]() ![]() Common symptoms include fatigue, headaches, muscle aches, joint pain, diarrhea, insomnia, and cognitive impairment. Gulf War Illness (GWI) is a chronic multisymptom health condition affecting one-third of all veterans who served in the 1991 Gulf War, most of whom remain afflicted more than 30 years later. UC San Diego scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria. The study, which could lead to improved treatment strategies, also suggests that similar mitochondrial impairments might underlie other inflammation-marked conditions. Researchers from the University of California, San Diego, have discovered that Gulf War Illness (GWI), a chronic condition affecting veterans of the 1991 Gulf War, is primarily driven by impaired mitochondrial function, not inflammation as previously believed.
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